Direct flights from Buffalo to Knoxville
1 nonstop flight a week on 1 airline. Zero layovers — one hop from BUF to TYS.
Flight time: about 1h19m nonstop
Which days does it fly?
When does it fly?
Departure times in Buffalo local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| Republic Airways RPA9933 | 7:12a | 1h19m | Sat |
The route
One hop: BUF → TYSDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Buffalo (BUF) to Knoxville (TYS)
Buffalo Niagara International Airport (BUF) has 1 nonstop flight a week to Knoxville (TYS), operated by Republic Airways. No layovers, no connections — one hop out of BUF and you're there.
This route flies on Saturday — check the schedule grid above before you pick a travel day. Route data updated October 2026 from observed departures.
Route data updated October 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Buffalo to Knoxville?
The nonstop flight from Buffalo (BUF) to Knoxville (TYS) takes about 1h19m in the air, based on recently observed nonstop departures.