Direct flights from Des Moines to Chicago
69 nonstop flights a week on 2 airlines. Zero layovers — one hop from DSM to ORD.
Flight time: about 54m nonstop
Which days does it fly?
When does it fly?
Departure times in Des Moines local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| United UAL1824 | 6:07a | 54m | Tue |
| United UAL1824 | 6:30a | 54m | Thu, Sat |
| United UAL1824 | 6:36a | 54m | Mon |
| United UAL1824 | 6:45a | 41m | Sun |
| Republic Airways RPA4383 | 6:59a | 44m | Tue |
| Republic Airways RPA4383 | 7:12a | 49m | Thu–Fri |
| Republic Airways RPA4383 | 7:16a | 44m | Mon, Sun |
| United UAL1824 | 7:28a | 52m | Fri |
| Republic Airways RPA4383 | 7:50a | 43m | Sat |
| United UAL2668 | 7:58a | 55m | Mon, Tue, Sun |
| United UAL2668 | 8:09a | 54m | Wed, Sat |
| United UAL2668 | 8:16a | 54m | Thu–Fri |
| Republic Airways RPA4383 | 9:00a | 51m | Wed |
| United UAL1824 | 10:02a | 53m | Wed |
| American ENY3413 | 10:35a | 51m | Tue |
| SkyWest SKW4955 | 10:40a | 56m | Sat–Sun |
| SkyWest SKW4955 | 10:46a | 51m | Thu |
| SkyWest SKW4955 | 10:59a | 1h6m | Fri |
| United UAL2769 | 11:28a | 56m | Fri–Sat |
| United UAL2769 | 11:37a | 56m | Mon, Wed, Sun |
| United UAL2769 | 11:55a | 54m | Thu |
| United UAL2769 | 12:10p | 57m | Tue |
| SkyWest SKW4955 | 12:30p | 47m | Wed |
| SkyWest SKW4955 | 12:38p | 1h6m | Wed |
| SkyWest SKW4726 | 1:28p | 58m | Mon, Tue, Wed, Thu, Sat |
| SkyWest SKW4726 | 1:38p | 53m | Fri |
| SkyWest SKW4726 | 2:11p | 58m | Sun |
| SkyWest SKW4965 | 2:34p | 43m | Tue |
| SkyWest SKW4933 | 2:43p | 49m | Fri |
| SkyWest SKW4933 | 2:48p | 1h5m | Thu |
| SkyWest SKW4933 | 2:58p | 1h2m | Mon, Wed, Sat |
| SkyWest SKW4955 | 3:01p | 41m | Mon |
| United UAL312 | 3:42p | 55m | Mon, Wed, Fri, Sat, Sun |
| United UAL312 | 3:46p | 49m | Tue |
| United UAL312 | 3:56p | 57m | Thu |
| SkyWest SKW4933 | 4:08p | 46m | Sun |
| Republic Airways RPA4769 | 6:02p | 42m | Mon, Fri |
| Republic Airways RPA4769 | 6:08p | 1h5m | Wed, Sat, Sun |
| Republic Airways RPA4769 | 6:19p | 44m | Thu |
| SkyWest SKW4928 | 8:00p | 54m | Sat–Sun |
| SkyWest SKW4928 | 8:12p | 54m | Wed |
| SkyWest SKW4928 | 8:19p | 52m | Thu–Fri |
| SkyWest SKW4928 | 9:27p | 1h1m | Mon |
American
UnitedThe route
One hop: DSM → ORDDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Des Moines (DSM) to Chicago (ORD)
Des Moines International Airport (DSM) has 69 nonstop flights a week to Chicago (ORD), operated by American and United. No layovers, no connections — one hop out of DSM and you're there.
This route flies every day of the week, so any travel day works. Route data updated September 2026 from observed departures.
Route data updated September 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Des Moines to Chicago?
The nonstop flight from Des Moines (DSM) to Chicago (ORD) takes about 54m in the air, based on recently observed nonstop departures.
How long does it take to drive from Des Moines to Chicago?
Driving from Des Moines to Chicago takes about 4h 58m, covering roughly 334 miles. The nonstop flight takes about 54m.