Direct flights from Manchester to Chicago
21 nonstop flights a week on 1 airline. Zero layovers — one hop from MHT to ORD.
Flight time: about 2h12m nonstop
Which days does it fly?
When does it fly?
Departure times in Manchester local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| American ENY4150 | 7:08a | 2h15m | Wed–Fri |
| American ENY4150 | 7:20a | 2h4m | Tue, Sat |
| American ENY4150 | 7:34a | 2h2m | Mon |
| American ENY4150 | 9:28a | 2h32m | Sun |
| American ENY3921 | 12:18p | 2h18m | Mon, Tue, Fri |
| American ENY3921 | 12:26p | 1h56m | Sat |
| American ENY3921 | 12:38p | 2h8m | Wed |
| American ENY3921 | 1:02p | 2h17m | Thu, Sun |
| American ENY3720 | 6:02p | 2h16m | Mon, Thu, Fri, Sat |
| American ENY3720 | 6:09p | 2h16m | Wed |
| American ENY3720 | 6:29p | 1h58m | Tue |
| American ENY3720 | 7:23p | 2h7m | Sun |
American
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The route
One hop: MHT → ORDDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Manchester (MHT) to Chicago (ORD)
Manchester-Boston Regional Airport (MHT) has 21 nonstop flights a week to Chicago (ORD), operated by American. No layovers, no connections — one hop out of MHT and you're there.
This route flies every day of the week, so any travel day works. Route data updated September 2026 from observed departures.
Route data updated September 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Manchester to Chicago?
The nonstop flight from Manchester (MHT) to Chicago (ORD) takes about 2h12m in the air, based on recently observed nonstop departures.
How long does it take to drive from Manchester to Chicago?
Driving from Manchester to Chicago takes about 15h 15m behind the wheel — roughly 1,017 miles, or about 2 days of real driving. The nonstop flight takes about 2h12m.