Direct flights from Charlotte to Knoxville
59 nonstop flights a week on 1 airline. Zero layovers — one hop from CLT to TYS.
Flight time: about 35m nonstop
Which days does it fly?
When does it fly?
Departure times in Charlotte local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| American JIA5232 | 8:03a | 29m | Sat |
| American PDT6093 | 8:25a | 31m | Sun |
| American PDT6094 | 8:42a | 34m | Wed–Thu |
| American PDT6094 | 8:47a | 54m | Mon, Fri, Sat |
| American PDT6094 | 8:59a | 37m | Tue |
| American JIA9954 | 9:04a | 31m | Sun |
| American JIA9954 | 9:41a | 30m | Sat |
| American PDT6094 | 9:49a | 40m | Sun |
| American PDT5898 | 10:51a | 30m | Wed |
| American PDT5898 | 11:12a | 31m | Mon |
| American PDT5898 | 11:20a | 30m | Thu–Sat |
| American PDT5791 | 11:39a | 31m | Sun |
| American PDT5791 | 11:52a | 56m | Tue |
| American PDT5851 | 12:32p | 33m | Mon, Thu |
| American PDT5851 | 12:37p | 30m | Tue, Wed, Fri |
| American PDT5851 | 12:52p | 36m | Sat |
| American PDT6097 | 2:23p | 33m | Mon, Fri |
| American PDT6097 | 2:29p | 40m | Sat–Sun |
| American PDT6097 | 2:36p | 30m | Tue, Thu |
| American JIA5199 | 3:25p | 37m | Sun |
| American PDT6097 | 4:35p | 37m | Wed |
| American SKW6350 | 4:44p | 27m | Sun |
| American JIA5584 | 4:48p | 47m | Mon, Sat |
| American JIA5584 | 5:06p | 37m | Tue |
| American JIA5584 | 5:21p | 37m | Thu |
| American JIA5584 | 5:26p | 46m | Wed, Fri |
| American PDT5901 | 5:53p | 37m | Tue |
| American PDT5901 | 6:01p | 46m | Wed–Thu |
| American PDT5901 | 6:26p | 31m | Mon |
| American PDT5901 | 6:44p | 24m | Fri |
| American PDT5901 | 6:56p | 33m | Sat |
| American PDT5901 | 7:52p | 31m | Sun |
| American JIA5368 | 8:24p | 29m | Mon |
| American JIA5368 | 8:30p | 37m | Tue, Sat |
| American JIA5368 | 8:35p | 36m | Wed |
| American JIA5368 | 8:54p | 36m | Fri |
| American JIA5368 | 9:40p | 35m | Thu |
| American JIA5232 | 9:54p | 51m | Mon |
| American JIA5232 | 10:12p | 29m | Tue–Thu |
| American JIA5368 | 10:25p | 38m | Sun |
| American JIA5232 | 10:31p | 34m | Sat |
| American JIA5232 | 11:30p | 36m | Sun |
American
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The route
One hop: CLT → TYSDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Charlotte (CLT) to Knoxville (TYS)
Charlotte Douglas International Airport (CLT) has 59 nonstop flights a week to Knoxville (TYS), operated by American. No layovers, no connections — one hop out of CLT and you're there.
This route flies every day of the week, so any travel day works. Route data updated September 2026 from observed departures.
Route data updated September 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Charlotte to Knoxville?
The nonstop flight from Charlotte (CLT) to Knoxville (TYS) takes about 35m in the air, based on recently observed nonstop departures.
How long does it take to drive from Charlotte to Knoxville?
Driving from Charlotte to Knoxville takes about 3h 55m — roughly 230 miles — so the car is a real alternative on this route. The nonstop flight takes about 35m.