Direct flights from Knoxville to Charlotte
59 nonstop flights a week on 1 airline. Zero layovers — one hop from TYS to CLT.
Flight time: about 39m nonstop
Which days does it fly?
When does it fly?
Departure times in Knoxville local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| American PDT5847 | 5:21a | 52m | Tue |
| American JIA5103 | 6:22a | 44m | Thu |
| American JIA5103 | 6:26a | 30m | Wed, Fri, Sat |
| American JIA5103 | 6:41a | 24m | Mon |
| American JIA5103 | 8:11a | 39m | Sun |
| American JIA5641 | 8:23a | 53m | Thu |
| American JIA5641 | 8:30a | 42m | Mon, Fri |
| American PDT5824 | 8:31a | 34m | Wed |
| American JIA5641 | 8:35a | 30m | Sat |
| American JIA5182 | 8:48a | 26m | Tue |
| American JIA9953 | 9:53a | 35m | Sat |
| American PDT6093 | 10:10a | 52m | Tue |
| American PDT6094 | 10:24a | 37m | Wed |
| American PDT6094 | 10:27a | 35m | Fri |
| American JIA5176 | 10:28a | 39m | Sun |
| American PDT6094 | 10:36a | 40m | Mon, Sat |
| American PDT6094 | 10:46a | 32m | Thu |
| American PDT6094 | 11:06a | 28m | Sun |
| American JIA5641 | 11:36a | 23m | Wed |
| American PDT5938 | 12:14p | 46m | Mon |
| American PDT6094 | 12:15p | 47m | Tue |
| American PDT5938 | 12:21p | 46m | Wed, Thu, Sat |
| American PDT5822 | 1:11p | 44m | Sun |
| American PDT5938 | 1:44p | 29m | Fri |
| American PDT5851 | 1:57p | 46m | Wed |
| American PDT6096 | 2:01p | 47m | Tue |
| American PDT5851 | 2:10p | 46m | Mon, Sat |
| American PDT5851 | 2:16p | 37m | Thu–Fri |
| American JIA9955 | 3:23p | 33m | Sun |
| American PDT6097 | 4:00p | 36m | Mon, Wed, Thu, Fri, Sat, Sun |
| American PDT6097 | 4:27p | 44m | Tue |
| American JIA5641 | 5:05p | 45m | Sun |
| American JIA5584 | 6:11p | 32m | Sat |
| American SKW6281 | 6:15p | 51m | Tue |
| American JIA5584 | 6:17p | 33m | Wed–Fri |
| American SKW6350 | 6:22p | 29m | Sun |
| American JIA5584 | 6:42p | 26m | Mon |
| American PDT5901 | 7:40p | 52m | Thu–Fri |
| American PDT5901 | 7:47p | 52m | Sat |
| American PDT6098 | 7:49p | 47m | Tue |
| American PDT5901 | 8:02p | 46m | Mon |
| American PDT5901 | 9:44p | 48m | Sun |
| American PDT6093 | 10:54p | 26m | Sun |
American
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The route
One hop: TYS → CLTDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Knoxville (TYS) to Charlotte (CLT)
McGhee Tyson Airport (TYS) has 59 nonstop flights a week to Charlotte (CLT), operated by American. No layovers, no connections — one hop out of TYS and you're there.
This route flies every day of the week, so any travel day works. Route data updated September 2026 from observed departures.
Route data updated September 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Knoxville to Charlotte?
The nonstop flight from Knoxville (TYS) to Charlotte (CLT) takes about 39m in the air, based on recently observed nonstop departures.
How long does it take to drive from Knoxville to Charlotte?
Driving from Knoxville to Charlotte takes about 3h 55m — roughly 230 miles — so the car is a real alternative on this route. The nonstop flight takes about 39m.