Direct flights from Chicago to Greenville-Spartanburg
27 nonstop flights a week on 2 airlines. Zero layovers — one hop from ORD to GSP.
Flight time: about 1h18m nonstop
Which days does it fly?
When does it fly?
Departure times in Chicago local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| Republic Airways RPA3633 | 6:38a | 1h18m | Mon, Fri |
| Republic Airways RPA3633 | 6:51a | 1h18m | Tue–Wed |
| American ENY4160 | 8:14a | 1h37m | Wed |
| American ENY4160 | 8:25a | 1h18m | Tue |
| Republic Airways RPA3633 | 9:02a | 1h18m | Thu |
| American ENY4002 | 10:02a | 1h23m | Wed |
| American ENY4002 | 10:31a | 1h30m | Thu |
| GoJet GJS4434 | 10:32a | 1h18m | Mon |
| GoJet GJS4434 | 10:38a | 1h18m | Fri |
| American ENY4002 | 10:58a | 1h23m | Tue |
| SkyWest SKW5591 | 2:17p | 1h2m | Mon |
| Republic Airways RPA3493 | 2:32p | 1h21m | Fri |
| SkyWest SKW5591 | 2:53p | 1h9m | Tue |
| SkyWest SKW5591 | 2:55p | 1h18m | Fri |
| American ENY4145 | 3:28p | 1h24m | Wed |
| SkyWest SKW5591 | 3:44p | 1h18m | Wed |
| SkyWest SKW5591 | 3:54p | 46m | Thu |
| American ENY4145 | 4:44p | 1h22m | Tue |
| American ENY4145 | 6:24p | 1h18m | Thu |
| United UAL2628 | 6:37p | 1h20m | Mon |
| United UAL2628 | 6:54p | 1h21m | Wed |
| United UAL2628 | 7:07p | 1h17m | Tue |
| American ENY3668 | 7:39p | 1h22m | Wed |
| United UAL2628 | 8:10p | 1h21m | Thu |
| American ENY3668 | 8:23p | 1h36m | Tue |
American
UnitedThe route
One hop: ORD → GSPDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Chicago (ORD) to Greenville-Spartanburg (GSP)
Chicago O'Hare International Airport (ORD) has 27 nonstop flights a week to Greenville-Spartanburg (GSP), operated by American and United. No layovers, no connections — one hop out of ORD and you're there.
This route flies on Monday, Tuesday, Wednesday, Thursday and Friday — check the schedule grid above before you pick a travel day. Route data updated September 2026 from observed departures.
Route data updated September 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Chicago to Greenville-Spartanburg?
The nonstop flight from Chicago (ORD) to Greenville-Spartanburg (GSP) takes about 1h18m in the air, based on recently observed nonstop departures.
How long does it take to drive from Chicago to Greenville-Spartanburg?
Driving from Chicago to Greenville-Spartanburg takes about 11h 3m, covering roughly 708 miles. The nonstop flight takes about 1h18m.