Direct flights from Key West to Knoxville
2 nonstop flights a week on 1 airline. Zero layovers — one hop from EYW to TYS.
Flight time: about 2h12m nonstop
Flying back? Knoxville → Key West · 2 nonstop flights a week
Which days does it fly?
When does it fly?
Departure times in Key West local time, from flights observed over the last 7 days.
| Flight | Departs | Duration | Days |
|---|---|---|---|
| Allegiant AAY3037 | 9:14a | 2h3m | Fri |
| Allegiant AAY1405 | 10:54a | 2h20m | Mon |
Allegiant
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Other airports near Key West with nonstops to Knoxville
| Airport | Distance | Flights / wk |
|---|---|---|
| MIA — MiamiAmerican | 126 mi | 8 |
| FLL — Fort LauderdaleAllegiant | 145 mi | 13 |
The route
One hop: EYW → TYSDrag to pan · scroll with ⌘/Ctrl to zoom · arrow keys when focused
Nonstop from Key West (EYW) to Knoxville (TYS)
Key West International Airport (EYW) has 2 nonstop flights a week to Knoxville (TYS), operated by Allegiant. No layovers, no connections — one hop out of EYW and you're there.
This route flies on Monday and Friday — check the schedule grid above before you pick a travel day. Route data updated October 2026 from observed departures.
Route data updated October 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.
How long is the flight from Key West to Knoxville?
The nonstop flight from Key West (EYW) to Knoxville (TYS) takes about 2h12m in the air, based on recently observed nonstop departures.
How long does it take to drive from Key West to Knoxville?
Driving from Key West to Knoxville takes about 15h 45m behind the wheel — roughly 1,034 miles, or about 2 days of real driving. The nonstop flight takes about 2h12m.
Is there a nonstop return flight from Knoxville to Key West?
Yes — 2 nonstop flights a week from Knoxville (TYS) back to Key West (EYW) on Allegiant, based on recently observed departures.