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McGhee Tyson Airport · TYS → MDW

Direct flights from Knoxville to Chicago

2 nonstop flights a week on 1 airline. Zero layovers — one hop from TYS to MDW.

Flight time: about 1h15m nonstop

Which days does it fly?

When does it fly?

Departure times in Knoxville local time, from flights observed over the last 7 days.

FlightDepartsDurationDays
Allegiant AAY3040 11:04a 1h12m Fri
Allegiant AAY1414 11:34a 1h17m Mon

The route

One hop: TYS → MDW

Nonstop from Knoxville (TYS) to Chicago (MDW)

McGhee Tyson Airport (TYS) has 2 nonstop flights a week to Chicago (MDW), operated by Allegiant. No layovers, no connections — one hop out of TYS and you're there.

This route flies on Monday and Friday — check the schedule grid above before you pick a travel day. Route data updated October 2026 from observed departures.

Route data updated October 2026 from observed flight departures. Schedules change — always confirm with the airline before booking.

How long is the flight from Knoxville to Chicago?

The nonstop flight from Knoxville (TYS) to Chicago (MDW) takes about 1h15m in the air, based on recently observed nonstop departures.

How long does it take to drive from Knoxville to Chicago?

Driving from Knoxville to Chicago takes about 8h 9m, covering roughly 541 miles. The nonstop flight takes about 1h15m.

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